drugset / Trial / NCT05670509

Intranasal vs Buccal vs Intramuscular Midazolam for the Home and Emergency Treatment of Acute Seizures

NCT05670509

Phase 4 Completed 305 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelTreatment

Summary

A randomized controlled clinical trial comparing patient/ ER physician satisfaction and ease of administration of 3 non IV routes of midazolam as a rescue medication for seizure control. Study population included children with known seizure disorder who were prescribed midazolam by pediatric neurologist at home and those presenting to ER with following inclusion and exclusion criteria

Timeline

Start
2019-01-19
Primary completion
2022-07-31
Completion
2022-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Midazolam Small molecule 0.2 mg/kg Intranasal

Indications