drugset / Trial / NCT05672121

Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

NCT05672121 ↗

Phase 1/2 Recruiting 42 enrolled Chengdu Origen Biotechnology Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

KH631 is a adeno-associated virus (AAV) vector-based gene therapy for subretinal injection. The long-term, stable therapeutic protein after one time injection for nAMD could potentially reduce the treatment burden and maintain vision.

Timeline

Start
2023-02-06
Primary completion
2026-12-28
Completion
2026-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject KH631 Gene therapy (AAV / viral vector) 0.2 ml Other