Oral Vitamin D2 for Prevention of COVID-19

Summary

A total of 218 participants will be included in this study, and will be randomly assigned 1:1 to the group taking vitamin D2 and the group not taking vitamin D2. Participants in the group taking vitamin D2 orally will receive 200,000 IU of vitamin D2 on the first day of the trial, and again two weeks later (200,000 IU) . The group that will not receive vitamin D2 will not receive any intervention. The whole trial will laste four weeks.

Timeline

Start

2022-12-18

Primary completion

2023-01-19

Completion

2023-02-20

Publications

• Wang H, Liu H, Huang J, Meng X, Wang W, Xiao W, Liu D, Tao L, Song C. Comparative Effects of Minodronate and Alendronate on Low Back Pain in Postmenopausal Osteoporosis and Age Influence: A Head-to-Head, Randomized Clinical Trial. Clin Interv Aging. 2025 Nov 27;20:2219-2230. doi: 10.2147/CIA.S541940. eCollection 2025.
• Wang H, Tao L, Cui L, Chen Y, Liu D, Xue L, Yang Y, Lv Y, Zhang F, Wang T, Wang X, Yuan W, Liu H, Huang J, Jiang Y, Liu N, Yang L, Hu Y, Li Y, Gao Y, Li H, Li B, Song C. Randomized trial of influence of vitamin D on the prevention and improvement of symptomatic COVID-19. Sci Rep. 2024 Sep 3;14(1):20519. doi: 10.1038/s41598-024-66267-8.

Drugs

Indications

No indication recorded.