IV and Intrathecal Ketamine in Cesarean Section

Phase 4 Completed 60 enrolled Assiut University

NaParallel-groupTriple-blindPrevention

Summary

In the current study, the investigators will compare the effects of low-dose intravenous (i.v.) ketamine versus intrathecal Ketamine added to spinal anesthesia on the time to first request for analgesia and maternal pain scores and overall satisfaction in patients undergoing cesarean section.

Timeline

Start: 2023-02-01
Primary completion: 2024-10-31
Completion: 2024-10-31

Publications

Background Abd El-Rahman AM, Mohamed AA, Mohamed SA, Mostafa MAM. Effect of Intrathecally Administered Ketamine, Morphine, and Their Combination Added to Bupivacaine in Patients Undergoing Major Abdominal Cancer Surgery a Randomized, Double-Blind Study. Pain Med. 2018 Mar 1;19(3):561-568. doi: 10.1093/pm/pnx105.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ketamine	Small molecule	0.1 mg/kg	Intrathecal
Comparator	Ketamine	Small molecule	0.25 mg/kg	Intrathecal

Indications

No indication recorded.