drugset / Trial / NCT05680558

Photopheresis in Early-stage Mycosis Fungoides

NCT05680558

Phase 2 Recruiting 74 enrolled Columbia University Mallinckrodt · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether photopheresis therapy can be used to improve the clinical course of early stage cutaneous T-cell lymphoma (CTCL). Currently, photopheresis is performed as a palliative treatment for late stage CTCL. However, recent studies have demonstrated that patients with early stage CTCL may have markers in their blood which were previously observed primarily in late stage disease, such as clonal T cell populations. Considering these findings, the study aims to investigate whether photopheresis therapy may be used earlier in the disease course to produce a clinical response.

Timeline

Start
2021-05-08
Primary completion
2027-03
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Methoxsalen Other / unclassified

Indications