drugset / Trial / NCT05680922

DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer

NCT05680922 ↗

Phase 1 Active not recruiting 41 enrolled Legend Biotech USA Inc
NaSingle-groupOpen-labelTreatment

Summary

This is a phase 1, first-in-human, open-label, multicenter, dose escalation and expansion study of DLL3-targeted chimeric antigen receptor T-cells in subjects with extensive stage small cell lung cancer or large cell neuroendocrine lung cancer.

Timeline

Start
2023-07-26
Primary completion
2027-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject LB2102 Cell therapy — —