drugset / Trial / NCT05685719
A Study to Evaluate the Relative Bioavailability of STI-1558 and the Effect of Itraconazole and Rifampin on the Pharmacokinetics of STI-1558
RandomizedCrossoverOpen-labelOther
Summary
This is an open-label study. This study includes 2 parts, in which part 1 is a relative BA study, Part 2 is a DDI study. Part 1 and Part 2 could be performed in parallel.
Timeline
- Start
- 2023-01-04
- Primary completion
- 2023-03-15
- Completion
- 2023-11-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
| Subject | Rifampicin | Small molecule | 600 mg | Oral |
| Subject | STI-1558 | Small molecule | 100 mg | Oral |
| Subject | STI-1558 | Small molecule | 200 mg | Oral |
| Subject | STI-1558 | Small molecule | 600 mg | Oral |