drugset / Trial / NCT05689983
Symptom-driven ICS/LABA Therapy for Adolescent Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Phase 1/2
Active not recruiting
40 enrolled
Washington University School of Medicine
National Center for Advancing Translational Sciences (NCATS) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupOpen-labelOther
Summary
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations. Unfortunately, prior interventions to improve inhaler nonadherence have shown a lack of long-term success. This study proposes to assess the problem of non-adherence using a D\&I research lens while testing a new inhaler approach to potentially ameliorate the detrimental consequences of maintenance inhaler nonadherence.
Timeline
- Start
- 2022-04-01
- Primary completion
- 2025-12-01
- Completion
- 2025-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Budesonide | Small molecule | — | Inhaled |
| Comparator | Fluticasone propionate | Other / unclassified | — | Inhaled |
| Comparator | Formoterol | Other / unclassified | — | Inhaled |