drugset / Trial / NCT05692024
COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
Phase 1/2
Recruiting
80 enrolled
Massachusetts General Hospital
National Cancer Institute (NCI) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery, chemotherapy and radiotherapy) for stage I-III colorectal cancer.
Timeline
- Start
- 2024-03-21
- Primary completion
- 2028-03-31
- Completion
- 2028-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | coffee | Unknown | 6 g | Oral |