Preterm Neonates Brain Ultrasound With CEUS and Elastography
Summary
The aim of the study is to investigate levels of brain perfusion and elasticity in preterm neonates when they reach the estimated due date and to compare the data with magnetic resonance imaging at term. Contrast enhanced ultrasound (sulphur hexafluoride) and ultrasound-assisted elastography will be used to evaluate the state of brain perfusion with ultrasound. Different appropriate imaging sequences will be used regarding MRI, including asl-perfusion. Neonates recruited from the Neonatal Intensive Care Unit (NICU) of Turku University Hospital will be recruited.
Timeline
- Start
- 2024-01-01
- Primary completion
- 2026-01
- Completion
- 2026-01
Outcome
Outcome not reported
Stopped (Enrollment): “The recruitment conditions could'n be met, because the clinically based treatment plans were changed before the beginning of recruitment and the ex-preemies didn't have venous access at the time of examinations.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lumason | Diagnostic / imaging agent | — | Intravenous |
Indications
No indication recorded.