drugset / Trial / NCT05700955

Neoadjuvant Chemoimmunotherapy in Recurrent Glioblastoma

NCT05700955 ↗

Phase 1 Unknown 30 enrolled University of Louisville
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The primary purpose of this study is to test the safety of Pembrolizumab and Temozolomide in treating recurrent glioblastoma and to characterize the effect of this treatment on the participants tumor and immune system..

Timeline

Start
2022-11-01
Primary completion
2025-01
Completion
2025-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous
Subject Temozolomide Small molecule — Oral

Indications