A Study of the Effect of Daridorexant on Nighttime Body Posture, the Noise Level Required to Wake up, and the Ability to Remember Words Previously Presented

Phase 1 Completed 36 enrolled Idorsia Pharmaceuticals Ltd.

RandomizedCrossoverQuadruple-blindOther

Summary

Timeline

Start: 2023-01-05
Primary completion: 2023-04-25
Completion: 2023-04-25

Publications

Magliocca M, Koopmans I, Vaillant C, Lemoine V, Zuiker R, Dingemanse J, Muehlan C. Nighttime safety of daridorexant: Evaluation of responsiveness to an external noise stimulus, postural stability, walking, and cognitive function. J Psychopharmacol. 2025 Mar;39(3):223-232. doi: 10.1177/02698811241293997. Epub 2024 Dec 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Daridorexant	Small molecule	25 mg	Oral
Subject	Daridorexant	Small molecule	50 mg	Oral

Indications

No indication recorded.