drugset / Trial / NCT05704361

A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis

NCT05704361 ↗

Phase 1 Recruiting 129 enrolled Hoffmann-La Roche
Non-randomizedSequentialOpen-labelTreatment

Summary

The primary purpose of the study is to evaluate the safety and tolerability of a single-ascending intravenous (IV) dose (Part 1), a single-ascending subcutaneous (SC) dose (Part 2), and multiple ascending SC doses (Part 3) of RO7121932 in participants with multiple sclerosis (MS).

Timeline

Start
2021-08-11
Primary completion
2027-07-08
Completion
2027-07-08

Drugs

EvaluationDrugModalityDoseRoute
Subject RO7121932 Unknown 7 mg Intravenous
Subject RO7121932 Unknown 70 mg Intravenous
Subject RO7121932 Unknown 200 mg Intravenous
Subject RO7121932 Unknown 700 mg Intravenous
Subject RO7121932 Unknown 2000 mg Intravenous

Indications