Impact of Hesperetin in Combination With Sucrose on Energy Metabolism

Summary

The aim of this cross-over intervention study is to investigate the influence of the sweet-modulating substance hesperetin in combination with sucrose in comparison to an equally sweet-tasting sucrose-only solution on markers of energy metabolism.

Timeline

Start

2023-01-31

Primary completion

2023-06-30

Completion

2023-11-15

Publications

• Gaider M, Kimmeswenger I, Schmidt J, Thines C, Wu A, Stoffl TK, Rust P, Ley JP, Krammer GE, Somoza V, Lieder B. Sucrose reduction with maintained sweetness level lowers glycemic fluctuations and energy intake in healthy males. Front Nutr. 2025 Nov 3;12:1682297. doi: 10.3389/fnut.2025.1682297. eCollection 2025.

Drugs

Indications