drugset / Trial / NCT05706350
Plant Stanol Esters and Influenza Vaccination
RandomizedParallel-groupTriple-blindPrevention
Summary
Plant stanols are known to lower low-density lipoprotein cholesterol (LDL-C). However, recent studies have suggested that these compounds also beneficially influence the immune system, e.g. increasing vaccine-specific antibody titers. BMI and age have previously been negatively associated to vaccination responses. If plant stanols indeed have beneficial effects on the immune system, people with overweight or obesity and higher age might benefit from consuming plant stanols prior to receiving the influenza vaccination.
Timeline
- Start
- 2022-10-11
- Primary completion
- 2022-12-20
- Completion
- 2022-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | plant stanols | Other / unclassified | 2 g | — |
| Subject | plant stanols | Other / unclassified | 3 g | — |
| Subject | plant stanols | Other / unclassified | 4 g | — |
| Background | Influenza Virus Vaccine | Vaccine | — | — |
Indications
No indication recorded.