drugset / Trial / NCT05707741

Dexmetomedine for Post Operative Delirium in Elderly Patients Undergoing Elective Total Knee Replacement Under Spinal Anesthesia

NCT05707741 ↗

Completed 45 enrolled Menoufia University
RandomizedParallel-groupSingle-blindPrevention

Summary

Postoperative delirium is a geriatric syndrome occurring after anesthesia and surgery which manifests as acute alterations in mental status, involving changes in cognition, attention, and levels of consciousness that tend to fluctuate The use of dexmedetomidine with the intention to prevent postoperative delirium remains controversial. Where it has shown to be effective in older adult patients undergoing cardiovascular and non-cardiovascular surgeries

Timeline

Start
2023-06-01
Primary completion
2024-02-02
Completion
2024-02-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator dexmetomedine Unknown 0.2 ug/kg —
Comparator dexmetomedine Unknown 0.4 ug/kg —

Indications