A GBT021601 ADME Microtracer Study in Healthy Volunteers

Summary

An Open-label Study of GBT021601 in 8 to 10 healthy male or female participants to evaluate the absorption, distribution, metabolism, and excretion (ADME) of GBT021601.

Timeline

Start

2022-12-22

Primary completion

2023-08-10

Completion

2023-08-10

Publications

• Zimmerman EI, Callegari E, Sharma R, Adenola A, Volpe J, Seetharaman K, Zhang C, Duchin K, Walker GS. A Phase 1 Microtracer Study Evaluating the Mass Balance, Excretion, and Pharmacokinetics of Osivelotor in Healthy Participants. Clin Transl Sci. 2026 Jun;19(6):e70601. doi: 10.1111/cts.70601.

Drugs

Indications