drugset / Trial / NCT05720273

Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients

NCT05720273

Phase 4 Unknown 80 enrolled Xiaoyan Jia
NaSingle-groupOpen-labelOther

Summary

The goal of this observational study or clinical trial is to learn about the effect of neutrophil gelatinase-associated lipocalin (NGAL) on vascular calcification in maintenance hemodialysis patients with secondary hyperparathyroidism (SHPT). The main question it aims to answer is: the predictive effects of blood NGAL level on the efficacy of palicalcitol in the treatment of SHPT and the adverse reactions of vascular calcification progression. Participants will be treated with palicalcitol, followed up and undergo routine series of Chronic Kidney Disease-Mineral and Bone Disorder associated tests before and after treatment.

Timeline

Start
2023-04-01
Primary completion
2024-03-31
Completion
2025-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Calcitriol Small molecule

Indications