drugset / Trial / NCT05720533

Disitamab Vedotin Combined With Sintilimab as First-line Treatment of Elderly Patients With Gastric Cancer

NCT05720533

NaSingle-groupOpen-labelTreatment

Summary

This study aims to explore the safety and efficacy of Disitamab vedotin combined with Sintilimab in elderly patients with HER2 overexpression Gastric Cancer. This is a single-arm exploratory clinical study. 20 patients with eHER2 overexpression gastric cancer are scheduled to be enrolled. Treatment regimen is Disitamab vedotin 2.5mg/kg and Sintilimab 200mg every 21 days, until disease progression or intolerable adverse reactions or death.

Timeline

Start
2023-03-01
Primary completion
2024-03-01
Completion
2025-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Disitamab Vedotin Monoclonal antibody 2.5 mg/kg Intravenous
Subject Sintilimab Monoclonal antibody 200 mg Intravenous

Indications