The Effectiveness of Epidermal Growth Factor Serum in Improve Facial Skin Hydration, Elasticity, Pigmentation, and Wrinkles.
Summary
EGF is a polypeptide that promotes cell differentiation and collagen production while decreasing melanin production. This study is designed to study its effectiveness in improving the texture and appearance of facial skin after daily topical application. We hypothesized that EGF would improve facial skin hydration, elasticity, pigmentation, and wrinkles.
Timeline
- Start
- 2023-01-30
- Primary completion
- 2024-06-05
- Completion
- 2024-12-12
Outcome
Missed primary endpoint
registry analysis (superiority test); Epidermal Growth Factor Serum Application; p = 1.000; Mean Difference (Final Values) 2.671; ANOVA NCT05724589 ↗
registry analysis (superiority test); Epidermal Growth Factor Serum Application; p = 0.096; Mean Difference (Final Values) -3.656; ANOVA NCT05724589 ↗
registry analysis (superiority test); Epidermal Growth Factor Serum Application; p = 0.169; Mean Difference (Final Values) -0.043; ANOVA NCT05724589 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | NEPIDERMIN | Protein / enzyme biologic | — | Topical |