drugset / Trial / NCT05726019
Colchicine in Patients Undergoing Coronary Artery Bypass Grafting After Acute Coronary Syndrome
RandomizedParallel-groupSingle-blindPrevention
Summary
The present study seeks to evaluate the effectiveness of the use of perioperative colchicine with regard to operative complications, in patients with acute coronary syndrome and indication for cardiac post-surgical revascularization. Patients will be selected and randomized while still in the emergency room and medication (colchicine 0.5mg every 12 hours or placebo) will be started within 24 hours of randomization, being maintained for 30 days after surgery.
Timeline
- Start
- 2022-02-05
- Primary completion
- 2025-12-21
- Completion
- 2025-12-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Colchicine | Small molecule | 0.5 mg | Oral |