drugset / Trial / NCT05726032

Empagliflozin in Patients With Cirrhosis and Ascites

NCT05726032

Phase 2 Recruiting 20 enrolled Yale University Boehringer Ingelheim · collab
RandomizedCrossoverTriple-blindOther

Summary

A proof-of-concept placebo-controlled trial to explore the acute and 14-day effects of empagliflozin on natriuresis and total body water in patients with cirrhosis and ascites. We will additionally investigate its effect on neurohumoral activation, and renal hemodynamics.

Timeline

Start
2023-09-11
Primary completion
2026-06-01
Completion
2026-06-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Empagliflozin Small molecule 10 mg