drugset / Trial / NCT05726253
Supportive Treatment and Antibiotics for Mild Pediatric Pneumonia
RandomizedParallel-groupQuadruple-blindOther
Summary
National guidelines make two recommendations for treatment of young children with mild pneumonia - one to avoid routine antibiotics and another to use narrow-spectrum antibiotics. No studies have compared the effectiveness of these two approaches. This pilot study will evaluate study processes and feasibility of a future clinical trial that proposes to test whether low-risk children managed as outpatients with mild community-acquired pneumonia (CAP) treated with supportive treatment without antibiotics will have a similar clinical response, with fewer adverse effects, compared with those treated with a supportive treatment plan that includes antibiotics.
Timeline
- Start
- 2023-01-09
- Primary completion
- 2023-12-31
- Completion
- 2023-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 80 mg/kg | Oral |
| Comparator | Amoxicillin | Other / unclassified | 100 mg/kg | Oral |