drugset / Trial / NCT05726253

Supportive Treatment and Antibiotics for Mild Pediatric Pneumonia

NCT05726253

RandomizedParallel-groupQuadruple-blindOther

Summary

National guidelines make two recommendations for treatment of young children with mild pneumonia - one to avoid routine antibiotics and another to use narrow-spectrum antibiotics. No studies have compared the effectiveness of these two approaches. This pilot study will evaluate study processes and feasibility of a future clinical trial that proposes to test whether low-risk children managed as outpatients with mild community-acquired pneumonia (CAP) treated with supportive treatment without antibiotics will have a similar clinical response, with fewer adverse effects, compared with those treated with a supportive treatment plan that includes antibiotics.

Timeline

Start
2023-01-09
Primary completion
2023-12-31
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amoxicillin Other / unclassified 80 mg/kg Oral
Comparator Amoxicillin Other / unclassified 100 mg/kg Oral

Indications