drugset / Trial / NCT05727943

Add-on Clioquinol in Drug-resistant Childhood Epilepsy: an Exploratory Study

NCT05727943

Phase 2 Unknown 10 enrolled KU Leuven
NaSingle-groupOpen-labelTreatment

Summary

In this exploratory trial, the potential anti-seizure activity of clioquinol in a small cohort of adolescents with drug-resistant epilepsy will be examined. Subjects will be exposed to clioquinol add-on for a period of maximum 8 weeks (2 weeks low dose, 6 weeks higher dose). The main hypothesis of the study is that 30% of the included subjects will be responders and that the median seizure frequency reduction will be at least 30%.

Timeline

Start
2022-03-01
Primary completion
2023-12-31
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Clioquinol Small molecule 4 mg/kg Oral

Indications