drugset / Trial / NCT05727943
Add-on Clioquinol in Drug-resistant Childhood Epilepsy: an Exploratory Study
NaSingle-groupOpen-labelTreatment
Summary
In this exploratory trial, the potential anti-seizure activity of clioquinol in a small cohort of adolescents with drug-resistant epilepsy will be examined. Subjects will be exposed to clioquinol add-on for a period of maximum 8 weeks (2 weeks low dose, 6 weeks higher dose). The main hypothesis of the study is that 30% of the included subjects will be responders and that the median seizure frequency reduction will be at least 30%.
Timeline
- Start
- 2022-03-01
- Primary completion
- 2023-12-31
- Completion
- 2023-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clioquinol | Small molecule | 4 mg/kg | Oral |