drugset / Trial / NCT05730816
MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI
Phase 2
Recruiting
130 enrolled
Brigham and Women's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
In this research study, investigators will test whether prophylactic high-dose IV Mg administration attenuates the risk of AKI in patients with malignant mesothelioma receiving intraoperative chemotherapy (HIOC) with cisplatin compared to placebo .
Timeline
- Start
- 2023-04-04
- Primary completion
- 2027-04-03
- Completion
- 2028-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Magnesium Sulfate | Other / unclassified | 1 g | Intravenous |