drugset / Trial / NCT05731518

SC0245 and Irinotecan in Treating Patients With Relapsed Extensive-Stage Small Cell Lung Cancer (ES-SCLC)

NCT05731518

Phase 1/2 Unknown 67 enrolled Biocity Biopharmaceutics Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

This study is a single arm, multi-center, open label phase Ib/II study of SC0245 and Irinotecan combination therapy in subjects with extensive-stage small cell lung cancer (ES-SCLC) as a second therapy. This study will have three parts, phase 1 dose escalation (Part 1), phase 1 dose expansion (Part 2), and phase 2 combination therapy (Part 3).

Timeline

Start
2023-02-23
Primary completion
2025-09-30
Completion
2026-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject SC0245 Unknown
Background Irinotecan Small molecule 80 mg/m2 Intravenous