drugset / Trial / NCT05732662

SBRT Combined With AK104 to Treatment Relapsed or Metastatic ESCC

NCT05732662 ↗

Phase 2 Not yet recruiting 25 enrolled The First People's Hospital of Changzhou
NaSingle-groupOpen-labelTreatment

Summary

The entire treatment process is divided into two phases: Phase I SBRT combined with PD-1/CTLA-4 bispecific antibody (AK104) and Phase II AK104 single-agent maintenance therapy.

Timeline

Start
2023-04
Primary completion
2025-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody 10 mg/kg —