drugset / Trial / NCT05733780
To Evaluate the Safety, Efficacy,and Pharmacokinetics of Orally Administered Prolectin-M
RandomizedParallel-groupTriple-blindPrevention
Summary
ProLectin M is an orally administered polysaccharide. Polysaccharides competitively bind to the N-terminal tail of human galectin-3 through a proline isomerization \[10\]. Galetin-3 (Gal-3) is 1 among the 15 galectins described in humans and also a ubiquitous human galectin expressed in various disease pathogenesis pathways \[11\]. The objective of this clinical study is to evaluate the safety and efficacy of a galectin antagonist, ProLectin M (a Guar Gum Galactomannan), in the treatment of subjects with asymptomatic to moderately-severe, ambulatory COVID-19 patients.
Timeline
- Start
- 2023-09
- Primary completion
- 2023-12
- Completion
- 2024-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Prolectin-M | Other / unclassified | 1400 mg | Oral |