drugset / Trial / NCT05737693
Enhancing Week-long Psychological Treatment for PTSD With Ketamine
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to test if the combination of ketamine, vs midazolam, with an intensive trauma-focused psychotherapy will be more effective in relieving post-traumatic stress disorder (PTSD). This week-long treatment has the potential to produce a significant therapeutic effect that otherwise would take months to occur. The study will also focus on learning about the neurophysiological changes produced by the proposed clinical trial.
Timeline
- Start
- 2023-08-21
- Primary completion
- 2030-08-01
- Completion
- 2031-08-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 0.2 mg/kg | Other |
| Subject | Ketamine | Small molecule | 0.5 mg/kg | Other |
| Comparator | Midazolam | Small molecule | 0.045 mg/kg | Other |