drugset / Trial / NCT05748145
Metronidazole as Preoperative Therapy in CRC / FusoMetro-001
NaSingle-groupOpen-labelOther
Summary
The proposed proof-of concept trial aims at determining the effectiveness of metronidazole in decreasing the Fusobacterium nucleatum load in tissues and possibly on its detrimental effects on tumor cells and tumor microenvironment.
Timeline
- Start
- 2023-09-11
- Primary completion
- 2026-12-31
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metronidazole | Small molecule | 500 mg | Oral |