Balanced Multi-Electrolyte Solution Versus Saline Trial for Diabetic KetoAcidosis

Summary

The goal of this blinded, cluster cross-over, randomised controlled trial is to determine whether fluid therapy with Plasma-Lyte® 148 increases the number of days alive and days out of hospital to day-28 compared to 0.9% sodium chloride ('0.9% saline') in critically ill patients presenting to the Emergency Department (ED) and deemed to require admission to a critical care area (ICU, HDU) with moderate to severe diabetic ketoacidosis (DKA).

Timeline

Start

2024-03-14

Primary completion

2026-07

Completion

2026-07

Drugs

Indications