drugset / Trial / NCT05757700

Study of 19(T2)28z1xx TRAC-Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Lymphoma

NCT05757700 ↗

Phase 1 Active not recruiting 30 enrolled Memorial Sloan Kettering Cancer Center Takeda · collab
NaSequentialOpen-labelTreatment

Summary

The purpose of this research is to evaluate if study therapy, 19(T2)28z1xx TRAC-chimeric antigen receptor (CAR) T cells, may be an effective treatment for people with relapsed/refractory B-cell lymphoma. Researchers will also evaluate if this study therapy is safe, and to look for the highest dose that causes few or mild side effects in participants.

Timeline

Start
2023-02-23
Primary completion
2027-02-23
Completion
2027-02-23

Drugs

EvaluationDrugModalityDoseRoute
Subject 19(T2)28z1xx TRAC T cell Cell therapy 3e+06 cells —
Subject 19(T2)28z1xx TRAC T cell Cell therapy 1e+07 cells —
Subject 19(T2)28z1xx TRAC T cell Cell therapy 3e+07 cells —
Subject 19(T2)28z1xx TRAC T cell Cell therapy 1e+08 cells —