drugset / Trial / NCT05763823

A Study of Letermovir (MK-8228) to Evaluate Efficacy and Safety for Prevention of Cytomegalovirus Infection in Chinese Hematopoietic Stem Cell Transplant Recipients (MK-8228-045)

NCT05763823

Phase 3 Completed 120 enrolled Merck Sharp & Dohme LLC
NaSingle-groupOpen-labelPrevention

Summary

The purpose of this study is to evaluate the efficacy and safety of a once-a-day oral or intravenous (IV) dose of Letermovir (MK-8228) in Chinese adult hematopoietic stem cell transplant (HSCT) recipients for the prevention of clinically significant cytomegalovirus (CMV) infection.

Timeline

Start
2023-03-24
Primary completion
2024-04-18
Completion
2024-04-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Letermovir Small molecule 240 mg Oral
Subject Letermovir Small molecule 480 mg Oral