drugset / Trial / NCT05765955

Effects of p38 MAPK Inhibitor POLB 001 on in Vivo LPS Challenge Responses

NCT05765955 ↗

Phase 1 Completed 36 enrolled Poolbeg Pharma plc
RandomizedParallel-groupDouble-blindTreatment

Summary

A single center trial to evaluate the effect of POLB 001 on inflammatory responses following an intradermal LPS challenge in healthy volunteers.

Timeline

Start
2022-07-22
Primary completion
2022-12-14
Completion
2022-12-16

Drugs

EvaluationDrugModalityDoseRoute
Comparator POLB 001 Unknown 30 mg —
Comparator POLB 001 Unknown 70 mg —
Comparator POLB 001 Unknown 150 mg —

Indications