drugset / Trial / NCT05770960
Colonic Motor Patterns in Healthy Volunteers
RandomizedCrossoverTriple-blindTreatment
Summary
Characterization of motor patterns with opioid agonists (codeine) ingestion, and their reversal by a peripherally acting mu-opioid receptor antagonist (Naloxegol).
Timeline
- Start
- 2018-06-27
- Primary completion
- 2019-05-09
- Completion
- 2019-05-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Codeine | Small molecule | — | Oral |
| Subject | Naloxegol | Small molecule | 25 mg | Oral |