The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension

Summary

Septic shock is defined as sepsis with persistent hypotension requiring vasopressors to maintain mean arterial pressure (MAP)≥ 65 mmHg and a serum lactate level of \> 2 mmol/L (18 mg/dL) despite sufficient volume resuscitation . Hypovolemia (both relative and absolute) and reduced vascular tone have a role in determining the severity of hypotension in septic shock

Timeline

Start

2021-05-01

Primary completion

2023-02-01

Completion

2023-03-10

Drugs

Indications