drugset / Trial / NCT05779059
Prasugrel Or Ticagrelor De-escalation in NSTE-ACS
RandomizedCrossoverOpen-labelTreatment
Summary
The PROTEUS study is a randomized, cross-over, open-label, pharmacodynamic trial designed to compare the antiplatelet effect of reduced maintenance doses of prasugrel and ticagrelor in stable patients who recently had non-ST-elevation acute coronary syndrome (non-ST-elevation myocardial infarction or unstable angina).
Timeline
- Start
- 2023-04-01
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Prasugrel | Small molecule | 5 mg | — |
| Subject | Ticagrelor | Small molecule | 60 mg | — |