drugset / Trial / NCT05784974

Cadonilimab Monotherapy as Neoadjuvant Therapy for Resectable II-IIIA Squamous Cell Lung Cancer

NCT05784974 ↗

Phase 2 Not yet recruiting 37 enrolled The First Hospital of Jilin University
NaSingle-groupOpen-labelTreatment

Summary

Cadonilimab, a tetravalent bispecific antibody targeting PD-1 and CTLA-4, is designed to retain the efficacy benefit of combination of PD-1 and CTLA-4 and improve on the safety profile of the combination therapy. The aim of this study is to evaluate the efficacy and safety of Cadonilimab monotherapy as neoadjuvant therapy for patients with resectable stage II-IIIA squamous cell lung cancer.

Timeline

Start
2023-05-01
Primary completion
2025-05-01
Completion
2028-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody 15 mg/kg Intravenous

Indications