drugset / Trial / NCT05789017
Treatment Strategies for IgG4-RD Patients With Internal Organ Involvement
RandomizedParallel-groupOpen-labelTreatment
Summary
This study has been designed as a 18-month, open-label randomized controlled clinical trial. The study aims to compare the efficacy and safety of two treatment strategies in active IgG4-RD patients with internal organ involvement during maintenance remission period: low dose mycophenolate mofetil group and leflunomide group.
Timeline
- Start
- 2022-07-01
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Leflunomide | Small molecule | 20 mg | — |
| Subject | Mycophenolate Mofetil | Small molecule | 1 g | — |
| Subject | Mycophenolate Mofetil | Small molecule | 1.5 g | — |
| Background | Prednisone | Other / unclassified | — | — |