drugset / Trial / NCT05789030

Treatment Strategies for IgG4-RD Patients With Superficial Organ Involvement

NCT05789030

Recruiting 60 enrolled Peking Union Medical College Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study has been designed as a 12-month, open-label randomized controlled clinical trial. The study aims to compare the efficacy and safety of two treatment strategies in IgG4-RD patients with superficial organ involvement: prednisone plus iguratimod and prednisone plus leflunomide.

Timeline

Start
2022-07-01
Primary completion
2026-04-30
Completion
2026-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Iguratimod Small molecule 25 mg
Subject Leflunomide Small molecule 10 mg
Subject Leflunomide Small molecule 20 mg
Background Prednisone Other / unclassified 5 mg

Indications