drugset / Trial / NCT05794971

Regorafenib Combined With Irinotecan Drug-Eluting Beads for Colorectal Cancer Liver Metastases

NCT05794971

Phase 3 Recruiting 126 enrolled Sun Yat-sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a multicentre, prospective, randomised trial, aims to evaluate the efficacy and safety of Irinotecan Drug-Eluting Beads combined with regorafenib as the third-line treatment for a patient with colorectal cancer liver metastases. The study is planned to enrolled 126 patients failing first- and second-line standard chemotherapy treatment.

Timeline

Start
2023-06-10
Primary completion
2027-03-31
Completion
2028-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule Other
Comparator Regorafenib Small molecule 80 mg Oral