drugset / Trial / NCT05803421

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk

NCT05803421

Phase 3 Completed 2749 enrolled Eli Lilly and Company
RandomizedParallel-groupOpen-labelTreatment

Summary

The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabetes and obesity or overweight at increased cardiovascular risk. The study will last approximately 2 years may include up to 27 visits.

Timeline

Start
2023-04-03
Primary completion
2026-03-16
Completion
2026-03-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Orforglipron Small molecule Oral
Comparator insulin glargine Protein / enzyme biologic Subcutaneous