drugset / Trial / NCT05808374
Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis B
RandomizedParallel-groupDouble-blindBasic science
Summary
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-5635 in healthy adults and chronic hepatitis B. To explore the reasonable dosage of HRS-5635.
Timeline
- Start
- 2023-04-30
- Primary completion
- 2024-05-31
- Completion
- 2024-05-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | HRS-5635 | Unknown | 50 mg | — |
| Subject | HRS-5635 | Unknown | 100 mg | — |
| Subject | HRS-5635 | Unknown | 200 mg | — |
| Subject | HRS-5635 | Unknown | 400 mg | — |
| Subject | HRS-5635 | Unknown | 600 mg | — |
| Subject | HRS-5635 | Unknown | 800 mg | — |