drugset / Trial / NCT05809934

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

NCT05809934 ↗

Phase 2 Completed 220 enrolled AstraZeneca
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 given by subcutaneous injection in adult participants with non-cirrhotic non-alcoholic steatohepatitis with fibrosis and who are carriers of the PNPLA3 148M Risk Allele

Timeline

Start
2023-03-15
Primary completion
2025-07-14
Completion
2025-09-29

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD2693 Antisense oligonucleotide — Subcutaneous