drugset / Trial / NCT05811351
A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to evaluate change in geographic atrophy (GA) lesion growth of eyes treated with JNJ-81201887 compared to sham control.
Timeline
- Start
- 2023-03-06
- Primary completion
- 2026-02-23
- Completion
- 2026-02-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AAVCAGsCD59 | Gene therapy (AAV / viral vector) | — | Intravitreal |
| Background | Prednisone | Other / unclassified | — | Oral |
| Background | Triamcinolone | Other / unclassified | — | Other |