drugset / Trial / NCT05812326
PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer
Phase 1/2
Completed
15 enrolled
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guangzhou Anjie Biomedical Technology Co., Ltd. · collab
NaSequentialOpen-labelTreatment
Summary
This exploratory clinical study aims to assess the safety and preliminary efficacy of an immunotherapy using PD-1 knockout anti-MUC1 CAR-T cells in the treatment of advanced MUC1-positive breast cancer
Timeline
- Start
- 2019-05-17
- Primary completion
- 2022-11-16
- Completion
- 2022-11-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AJMUC1 | Cell therapy | 300000 cells/kg | — |
| Subject | AJMUC1 | Cell therapy | 1e+06 cells/kg | — |
| Subject | AJMUC1 | Cell therapy | 3e+06 cells/kg | — |