Safety and Efficacy of RHH646 for Knee Osteoarthritis

Summary

The purpose of this study was to evaluate the articular cartilage-regenerating capacity of RHH646 in the knee as well as to assess safety and tolerability in participants with knee osteoarthritis.

Timeline

Start

2023-05-31

Primary completion

2025-02-24

Completion

2025-02-24

Outcome

Missed primary endpoint

registry analysis (superiority test); RHH646 75 mg vs Placebo; p = 0.0575 NCT05816395 ↗

Drugs

Indications