drugset / Trial / NCT05817240

A Drug-Drug Interaction Study of ENV-101 (Taladegib) on Nintedanib Pharmacokinetics in Healthy Subjects

NCT05817240

Phase 1 Completed 21 enrolled Endeavor Biomedicines, Inc.
NaSingle-groupOpen-labelOther

Summary

The goal of this clinical trial is to learn about the potential effect of ENV-101 (taladegib) on the pharmacokinetics of nintedanib (an approved treatment for idiopathic pulmonary fibrosis) when the two compounds are dosed together in healthy subjects. Participants in this study will receive ENV-101 and/or nintedanib on various days throughout a 10-day period during which they will reside at the clinical trial site.

Timeline

Start
2023-05-03
Primary completion
2023-06-11
Completion
2023-06-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Nintedanib Small molecule 100 mg
Subject taladegib Small molecule 100 mg