drugset / Trial / NCT05818618

Impact of Topical Clobetasol on Gingival Crevicular Fluid miRNAs in Subjects Affected by Oral Lichen Planus

NCT05818618

Completed 64 enrolled University of Catania
RandomizedParallel-groupDouble-blindTreatment

Summary

According to recent research, microRNAs (miRNAs) may function as early disease indicators and contribute to the severity of a number of precancerous and malignant oral disorders. The aim of the present study, through a double-blind randomized controlled trial design, is to analyze in the gingival crevicular fluid (GCF) as a non-invasive approach the impact of topical clobetasol on miRNAs expression in subjects affected by oral lichen planus (OLP).

Timeline

Start
2020-03-12
Primary completion
2023-07-05
Completion
2023-08-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator clobetasol propionate Small molecule 0.05 % Topical

Indications