drugset / Trial / NCT05824481

Study of Cadonilimab (AK104) Plus Lenvatinib in Patients With Advanced Endometrial Cancer

NCT05824481 ↗

Phase 2 Active not recruiting 32 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, multi-center Phase II study of cadonilimab (AK104) combined with lenvatinib in patients with advanced endometrial cancer. The primary objective is to evaluate objective response rate of cadonilimab plus lenvatinib.

Timeline

Start
2023-05-08
Primary completion
2025-07-31
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody 10 mg/kg Intravenous
Subject Lenvatinib Small molecule 12 mg Oral
Subject Lenvatinib Small molecule 16 mg Oral